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The most popular Southeast Missouri State University undergraduate major is General Studies. Biology/Biological Sciences, General and Psychology, General are other popular majors.
| General Studies | 118 |
| Biology/Biological Sciences, General | 99 |
| Psychology, General | 85 |
| Business Administration and Management, General | 83 |
| Registered Nursing/Registered Nurse | 80 |
| Speech Communication and Rhetoric | 77 |
| Agribusiness/Agricultural Business Operations | 59 |
| Corrections | 56 |
| Family and Consumer Sciences/Human Sciences, General | 55 |
| Visual and Performing Arts, General | 49 |
| Organizational Communication, General | 48 |
| Elementary Education and Teaching | 47 |
| Computer and Information Sciences, General | 41 |
| Early Childhood Education and Teaching | 40 |
| Communication Sciences and Disorders, General | 35 |
| Special Education and Teaching, General | 33 |
| Engineering Technology, General | 30 |
| Accounting | 29 |
| Computer and Information Systems Security/Information Assurance | 29 |
| Social Work | 28 |
| Health/Health Care Administration/Management | 27 |
| Music Teacher Education | 26 |
| Art/Art Studies, General | 22 |
| Industrial Technology/Technician | 22 |
| Marketing/Marketing Management, General | 22 |
| Plant Sciences, General | 21 |
| Finance, General | 19 |
| International/Global Studies | 18 |
| Political Science and Government, General | 18 |
| Health and Physical Education/Fitness, General | 17 |
| Health Services/Allied Health/Health Sciences, General | 16 |
| Social Sciences, General | 16 |
| Social Studies Teacher Education | 15 |
| Music, General | 13 |
| Chemistry, General | 12 |
| Hospitality Administration/Management, General | 12 |
| Economics, General | 11 |
| English Language and Literature/Letters, Other | 10 |
| Entrepreneurship/Entrepreneurial Studies | 9 |
| History, General | 9 |
| English/Language Arts Teacher Education | 8 |
| Environmental Science | 8 |
| Health Communication | 8 |
| Junior High/Intermediate/Middle School Education and Teaching | 8 |
| Sport and Fitness Administration/Management | 8 |
| Engineering Physics/Applied Physics | 7 |
| Parks, Recreation and Leisure Studies | 7 |
| Physical Education Teaching and Coaching | 7 |
| Family and Consumer Sciences/Home Economics Teacher Education | 6 |
| International Business/Trade/Commerce | 6 |
| Plant Sciences, General | 6 |
| Art Teacher Education | 5 |
| Biology/Biological Sciences, General | 5 |
| English Language and Literature, General | 5 |
| Fashion Merchandising | 5 |
| Historic Preservation and Conservation | 5 |
| Industrial Technology/Technician | 5 |
| Mathematics, General | 5 |
| Psychology, General | 5 |
| Systems Engineering | 5 |
| Agribusiness/Agricultural Business Operations | 4 |
| Athletic Training/Trainer | 4 |
| Clinical Laboratory Science/Medical Technology/Technologist | 4 |
| Political Science and Government, General | 4 |
| Science Teacher Education/General Science Teacher Education | 4 |
| Engineering/Industrial Management | 3 |
| Foreign Language Teacher Education | 2 |
| Marketing/Marketing Management, General | 2 |
| Mathematics, General | 2 |
| Multi-/Interdisciplinary Studies, Other | 2 |
| Physics, General | 2 |
| Aeronautical/Aerospace Engineering Technology/Technician | 1 |
| Agricultural Teacher Education | 1 |
| Apparel and Textile Marketing Management | 1 |
| Corrections | 1 |
| Crisis/Emergency/Disaster Management | 1 |
| Dietetics/Dietitian | 1 |
| English Language and Literature/Letters, Other | 1 |
| History, General | 1 |
| Interior Design | 1 |
| International/Global Studies | 1 |
| Mathematics Teacher Education | 1 |
| Music, General | 1 |
| Parks, Recreation and Leisure Studies | 1 |
| Physics, General | 1 |
| Social Sciences, General | 1 |
| Speech Communication and Rhetoric | 1 |
The data on this website is sourced as public domain data from the most recent survey year of the National Center for Education Statistics’ College Navigator tool. That tool can be found at this link: https://nces.ed.gov/collegenavigator/. MyCollegeSelection encourages students to explore multiple resources as part of the research process in selecting the college of their dreams.