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The most popular Missouri Southern State University undergraduate major is Business/Commerce, General. Liberal Arts and Sciences/Liberal Studies and Health Professions and Related Clinical Sciences, Other are other popular majors.
| Business/Commerce, General | 211 |
| Liberal Arts and Sciences/Liberal Studies | 90 |
| Biology/Biological Sciences, General | 78 |
| Criminal Justice/Law Enforcement Administration | 71 |
| Registered Nursing/Registered Nurse | 61 |
| Elementary Education and Teaching | 60 |
| Health Professions and Related Clinical Sciences, Other | 60 |
| Psychology, General | 41 |
| Secondary Education and Teaching | 28 |
| Sports, Kinesiology, and Physical Education/Fitness, Other | 28 |
| Environmental Health | 26 |
| Social Work | 23 |
| Speech Communication and Rhetoric | 23 |
| Computer and Information Sciences, General | 17 |
| English Language and Literature, General | 13 |
| Industrial Technology/Technician | 12 |
| Fine/Studio Arts, General | 11 |
| Sociology, General | 9 |
| Health/Health Care Administration/Management | 8 |
| Music Performance, General | 8 |
| Romance Languages, Literatures, and Linguistics | 8 |
| Junior High/Intermediate/Middle School Education and Teaching | 7 |
| International Policy Analysis | 5 |
| Drama and Dramatics/Theatre Arts, General | 4 |
| History, General | 4 |
| Logistics, Materials, and Supply Chain Management | 4 |
| Mathematics, General | 4 |
| Biology/Biological Sciences, General | 2 |
| Business, Management, Marketing, and Related Support Services, Other | 2 |
| Chemistry, General | 2 |
| Clinical Laboratory Science/Medical Technology/Technologist | 2 |
| Computer and Information Sciences, General | 2 |
| Acting | 1 |
| Art/Art Studies, General | 1 |
| Biochemistry | 1 |
| Criminal Justice/Law Enforcement Administration | 1 |
| Directing and Theatrical Production | 1 |
| History, General | 1 |
| Junior High/Intermediate/Middle School Education and Teaching | 1 |
| Psychology, General | 1 |
| Speech Communication and Rhetoric | 1 |
| Business/Managerial Economics | 0 |
| Geography | 0 |
| International Relations and Affairs | 0 |
| Physics, General | 0 |
| Political Science and Government, General | 0 |
The data on this website is sourced as public domain data from the most recent survey year of the National Center for Education Statistics’ College Navigator tool. That tool can be found at this link: https://nces.ed.gov/collegenavigator/. MyCollegeSelection encourages students to explore multiple resources as part of the research process in selecting the college of their dreams.