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The most popular East Tennessee State University undergraduate major is Registered Nursing/Registered Nurse. Psychology, General and Business Administration and Management, General are other popular majors.
| Registered Nursing/Registered Nurse | 502 |
| Psychology, General | 153 |
| Business Administration and Management, General | 133 |
| Computer and Information Sciences, General | 91 |
| Biology/Biological Sciences, General | 87 |
| Liberal Arts and Sciences/Liberal Studies | 84 |
| Criminal Justice/Law Enforcement Administration | 76 |
| Health and Physical Education/Fitness, General | 74 |
| Mass Communication/Media Studies | 73 |
| Marketing/Marketing Management, General | 71 |
| Teacher Education, Multiple Levels | 68 |
| Health Professions and Related Clinical Sciences, Other | 65 |
| Social Work | 63 |
| Finance, General | 57 |
| Animation, Interactive Technology, Video Graphics and Special Effects | 53 |
| Engineering Technology, General | 50 |
| Accounting | 49 |
| English Language and Literature, General | 47 |
| Sport and Fitness Administration/Management | 44 |
| History, General | 42 |
| Radiologic Technology/Science – Radiographer | 39 |
| Rehabilitation Science | 37 |
| Human Services, General | 36 |
| Child Development | 33 |
| Health/Health Care Administration/Management | 31 |
| Dental Hygiene/Hygienist | 29 |
| Geology/Earth Science, General | 28 |
| Chemistry, General | 23 |
| Art/Art Studies, General | 22 |
| Microbiology, General | 22 |
| Music, General | 22 |
| Political Science and Government, General | 22 |
| Dietetics/Dietitian | 21 |
| Interior Design | 20 |
| Rhetoric and Composition | 20 |
| Sociology | 19 |
| Respiratory Care Therapy/Therapist | 16 |
| Foreign Languages and Literatures, General | 14 |
| Surveying Technology/Surveying | 13 |
| Drama and Dramatics/Theatre Arts, General | 12 |
| Special Education and Teaching, General | 12 |
| Public Health, General | 11 |
| General Studies | 10 |
| Business/Managerial Economics | 9 |
| Mathematics, General | 9 |
| Musicology and Ethnomusicology | 8 |
| Pharmacy | 8 |
| Physics, General | 8 |
| International Relations and Affairs | 7 |
| Philosophy | 7 |
| Anthropology | 6 |
| Graphic Design | 6 |
| Psychology, General | 6 |
| International Relations and Affairs | 5 |
| Biology/Biological Sciences, General | 4 |
| Chemistry, General | 4 |
| Environmental Health | 4 |
| Criminal Justice/Law Enforcement Administration | 3 |
| Engineering, General | 3 |
| Engineering Technology, General | 2 |
| Finance, General | 2 |
| Health Professions and Related Clinical Sciences, Other | 2 |
| Physics, General | 2 |
| Sociology | 2 |
| Sport and Fitness Administration/Management | 2 |
| Accounting | 1 |
| Business Administration and Management, General | 1 |
| Drama and Dramatics/Theatre Arts, General | 1 |
| Economics, General | 1 |
| English Language and Literature, General | 1 |
| Foreign Languages and Literatures, General | 1 |
| Geology/Earth Science, General | 1 |
| Health and Physical Education/Fitness, General | 1 |
| Health/Health Care Administration/Management | 1 |
| Marketing/Marketing Management, General | 1 |
| Mathematics, General | 1 |
| Microbiology, General | 1 |
| Philosophy | 1 |
| Political Science and Government, General | 1 |
| Respiratory Care Therapy/Therapist | 1 |
| Rhetoric and Composition | 1 |
The data on this website is sourced as public domain data from the most recent survey year of the National Center for Education Statistics’ College Navigator tool. That tool can be found at this link: https://nces.ed.gov/collegenavigator/. MyCollegeSelection encourages students to explore multiple resources as part of the research process in selecting the college of their dreams.